Andromache (PBK) by Euripides, P. T. Stevens

By Euripides, P. T. Stevens

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We thank Dr. Paolo Gresele for PAF bioassays and Mr. Antonio Boila for technical assistance. REFERENCES 1. , and Tsukatani, H. (1987) Biochem. Biophys. Res. Commun. 145, 415–425. 2. , and Tsukatani, H. (1989) J. Lipid Res. 30, 219–224. 3. S. (1988) Biochim. Biophys. Acta 963, 375–383. 4. , and Camussi, G. (1986) J. Biol. Chem. 261, 16502–16508. 5. H. (1988) Science 240, 1792–1794. 6. G. (1987) Biochem. Biophys. Res. Commun. 149, 580–587. 7. G. (1970) Biochim. Biophys. Acta 149, 580–587. 8. , and Trovarelli, G.

The role of PAF in the nervous tissue is not known, but several reports have indicated that this lipid mediator may serve some function under physiological and pathological conditions. In fact, it has been shown by Bussolino and colleagues (4) that neurotransmitters induce PAF biosynthesis in chick retina. Furthermore, Kornecki and Ehrlich (5) have shown that, at nanomolar concentrations, PAF can stimulate morphological differentiation of neural cells, but becomes cytotoxic at higher concentrations.

Biol. Chem. 263, 1755–1760. 15. J. (1951) J. Biol. Chem. 193, 265–275. 16. , and Goracci, G. (1987) J. Liquid Chromat. 10, 2799–2808. 17. J. (1959) Can. J. Biochem. Physiol. 37, 911–917. 18. B. (1987) Pharmacol. Rev. 39, 97–145. 19. , and Cook, K. (1966) J. Biol. Chem. 241, 3390–3394. 20. , and Woelk, H. (1973) J. Neurochem. 21, 1067–1082. 21. , and Snyder, F. (1987) J. Biol. Chem. 262, 2520–2527. 22. A. (1985) Neurochem. Res. 10, 1445–1452. 23. , and Lee, T-c. (1984) Biochem. Biophys. Res. Commun.

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