Atlas of Hypertension by Norman K. Hollenberg (ed.)

By Norman K. Hollenberg (ed.)

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90 :c 100 80 c :li 70 90 W 00 ~ fO 0- ~ 50 -L------------------------------------------------~ 70 Wee Iy 3·h morning monitoring averages (n=6) 2-17. The blood pressure response to hindquarter compression in conscious dogs. A sustained increase in blood pressure in conscious dogs can be induced by prolonged hindquarter compression with an inflatable suit. This type of reflex blood pressure FIGURE 200 -r----- ------------------, r 100 150 E E :; '"'" 80 5. "8CD 120 -r--------- --------------, 100 60 elevation demonstrates that neurogenic elevation of blood pressure can be prolonged and reproducibly maintained over long periods of time.

Afferent input from periphery Reciprocal balance between sympathetic and parasympathetic tone 2-7. The central organization of the negative feedback loops in the autonomic nervous system. Inhibitory input from mechanoreceptors in the heart and aortic and carotid baroreceptors travels via afferent vagal fibers to the nucleus tractus solitarius (NTS). Sympathetic outflow is transmitted by efferent nerve fibers to the heart, blood vessels, and adrenal gland via the spinal cord. Cardiac parasympathetic tone originating from the vagal nuclei is modulated by the NTS in an integrated and reciprocal fashion.

Rapp JP: Characteristics of Dahl salt-susceptible and salt-resistant 29. Lifton RP: Molecular genetics of human blood pressure variation. rats. In Handbook of Hypertension. Vol 4. Experimental and Genetic Science 1996, 272:676-680. Models of Hypertension. Edited by de Jong W. New York: Elsevier 30. : Molecular basis Science Publishers; 1984:286-295. of human hypertension: role of angiotensinogen. Cell 1992, 11. : Brief angiotensin71:1-20. converting enzyme inhibitor treatment in young spontaneously 31.

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