Atlas of Mammalian Chromosomes by Stephen J. O'Brien (Editor), Joan C. Menninger (Editor),

By Stephen J. O'Brien (Editor), Joan C. Menninger (Editor), William G. Nash (Editor)

A gorgeous visible choice of the banded metaphase chromosome karyotypes from a few 850 species of mammals, the Atlas of Mammalian Chromosomes represents an unabridged compendium of the kingdom of this genomic artwork shape. Bringing jointly details at present scattered in the course of the cytogenetics literature for ratings of released and unpublished species, this atlas positive factors top quality karyotype photographs for almost each mammal studied up to now, making it the main accomplished assemblage of high-resolution chromosome pictures available--a seriously precious source for brand new comparative genomics era.For each on hand species, the Atlas of Mammalian Chromosomes offers the easiest karyotype produced, the typical and Latin identify of the species, the printed quotation, and the contributing authors. such a lot karyotypes are G-banded, revealing the chromosomal bar codes of homologous segments between comparable species.Addressing the mandate of the Human Genome venture to annotate the genomes of different organisms besides, the Atlas of Mammalian Chromosomes bargains a breakthrough in our knowing of species formation, of genome association, and of DNA script for common choice. it really is a useful source for geneticists, mammalogists, and biologists attracted to comparative genomics, systematics, and chromosome constitution.

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G-banding and cross-species chromosome painting have confirmed the remarkable homology of this 2n = 14 complement across five of these orders (Dasyuromorphia, Didelphimorphia, Diprotodontia, Microbiotheria, Peramelemorphia), including its almost complete conservation for ~70 million years in eight marsupial families (Dasyuridae, Peramelidae, Vombatidae, Burramyidae, Acrobatidae, Marmosidae, Caluromyidae, Microbiotheriidae). The presence of this extraordinarily similar 2n = 14 karyotype in highly divergent marsupial lineages from both Australasia and the Americas provides strong evidence that it represents the ancestral marsupial karyotype.

Full genome sequences of other mammalian species recently sequenced (mouse, rat, bovine, dog) showed that other mammals had very similar composition statistics and gene order, affirming the indisputable unity of all living mammals. Our genomes all descend from an ancient 200-million-year-old ancestor, the tiny insectivore of the Triassic. Comparative genomics of mammals is a fast-moving new field empowered by the vastness of genome information, by powerful computer routines developed to quantify DNA divergence, and by a potential to unlock the hidden secrets in the human and related species genomes.

MENNINGER WILLIAM G. NASH Frederick, Maryland February 2006 xxxiii ACKNOWLEDGMENTS W e wish to thank all those contributors (p. xxxvii) who donated their time, effort, and encouragement to this major collection of mammalian karyotypes. In particular we are indebted to all who cheerfully who sent reprints, karyotypes, electronic images, text, and other information incorporated in this edition. Without all the technical help and support from the collaborators and authors, this work would not have reached fruition.

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