Biotherapy: A Comprehensive Overview (Jones and Bartlett by Paula Trahan Rieger

By Paula Trahan Rieger

This article offers the root to appreciate and practice this healing modality. the talents essential to deal with sufferers who obtain it are incorporated. It additionally presents additional perception into the sphere of biotherapy, as good as a point of view of the information received up to now. management and nursing administration of BRM negative effects are delineated in addition to parts for destiny nursing examine. this article is meant for oncology nurses, yet others concerned with biotherapy will locate it to be a helpful source.

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To the authors, who shared their knowledge and expertise and worked hard to achieve the excellence I requested of them. To my husband, who accepted the many hours this project demanded from me and supported me by being the wonderful man that he is. And to my parents, who raised me to believe in myself and that I could achieve any goal I set my mind to. Page xix CONTRIBUTORS Lynne Brophy, RN, MSN, OCN Oncology Clinical Nurse Specialist Rex Hospital Raleigh, North Carolina Clinical Instructor Department of Adult and Geriatric Health School of Nursing University of North Carolina Chapel Hill, North Carolina Grace E.

In-depth discussion of the IFNs is found in Chapter 4. Interleukins Interleukins (ILs) can be produced by and regulate many cell types. In 1986, the Sixth International Congress of Immunology decided that new cytokines would be named according to their biological properties but that, on identification of the amino acid sequence, a sequential IL number would be assigned (Dinarello and Mier, 1987). Twelve ILs have so far been identified and isolated, and are undergoing either preclinical or clinical evaluation.

As a result of these advances, the Food and Drug Administration approved interferon-alpha in 1986, granulocyte and granulocyte-macrophage colony-stimulating factors in 1991, interleukin-2 in 1992, OncoScint® for monoclonal imaging of colon and ovarian cancer in 1992, and BCG for bladder cancer in 1990. Many more BRM agents are in various stages of development and testing and include growth and maturation factors, tumor vaccines, and gene therapy. Nurses have been significant contributors to the development of this fourth modality of cancer treatment, both in the conduct of clinical trials and the care of individuals receiving biotherapy.

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