Cardiac Drugs by Kanu Chatterjee

By Kanu Chatterjee

Cardiac medications describes the newest advances within the speedily evolving region of cardiovascular pharmacology. Written by way of popular, USbased specialists in cardiology, this booklet discusses the drug teams for various ailments, equivalent to acute coronary syndromes, high blood pressure, angina and center failure. Separate chapters learn cardiac medications in being pregnant and lactation, and destiny instructions. more desirable by means of complete color pictures and illustrations, this straightforward to keep on with textual content deals functional recommendation on easy methods to deal with cardiac ailments, with a spotlight on hands-on healing information for clinicians.

Show description

Read or Download Cardiac Drugs PDF

Similar cardiology books

The Official Patient's Sourcebook on Restrictive Cardiomyopathy

This ebook has been created for sufferers who've made up our minds to make schooling and study a vital part of the remedy technique. even though it additionally supplies info valuable to medical professionals, caregivers and different overall healthiness pros, it tells sufferers the place and the way to seem for info protecting almost all issues regarding restrictive cardiomyopathy (also cardiomyopathy - restrictive; infiltrative cardiomyopathy), from the necessities to the main complex parts of analysis.

Brain Protection in Cardiac Surgery: Volume 1

Mind harm continues to be the most dreaded issues of cardiac surgical procedure. the variety of damage is large; whereas a stroke can be simply outlined and clinically determined, extra refined accidents almost definitely ensue. There is still debate as to how those are clinically determined and there's a loss of regular definitions permitting inter-study comparability.

Basis and Treatment of Cardiac Arrhythmias

This ebook comprises the main up-to date info relating to mechanisms and therapy of cardiac arrhythmia. a number of the issues mentioned during this textual content mirror very lately undertaken learn instructions together with genetics of arrhythmias, telephone signalling molecules as power healing goals and trafficking to the membrane.


The 1st version of this guide seemed precisely twenty-five years in the past. because of huge, immense alterations within the zone of diuretics, the second one variation has needed to be thoroughly revised. sizeable growth has been made within the practical anatomy of the kidney and within the thoughts of ways elements and ions are in particular transported around the a variety of nephron segments.

Additional resources for Cardiac Drugs

Example text

Matrix degrading enzymes, matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9, are increased in thoracic and aortic aneurysms and have been suggested to be contributing factor in the pathogenesis of aortic aneurysms. In animal model, AT1 receptors blockade was associated with decreased expression of MMP-2 and MMP-9, which is another rationale for the use of AT1 receptors blocking agent for treatment of aortic aneurysms. ALDOSTERONE INHIBITORS: SPIRONOLACTONE AND EPLERENONE Introduction Aldosterone, a mineralocorticoid hormone and product of the RAAS, has been linked to hypertension, cardiac remodeling, and vascular fibrosis.

PRO. Cardiol Clin. 2010;28(2):273-7. 64. Cook JR, Nistala H, Ramirez F. Drug-based therapies for vascular disease in Marfan syndrome: from mouse models to human patients. Mt Sinai J Med. 2010;77(4):366-73. 65. Habashi JP, Doyle JJ, Holm TM, Aziz H, Schoenhoff F, Bedja D, et al. Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. Science. 2011;332(6027):361-5. 66. Fujiwara Y, Shiraya S Miyake T, Yamakawa S, Aoki M, Makino H, et al. Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan.

The dose of ARBs is largely based on clinical trials, and one dose does not fit all patients (Table 5). 51 It indicated that losartan at 150 mg/day reduced the rate of death or admission to the hospital for HF more than the commonly used dose of losartan 50 mg/day. This supports the value of uptitrating the ARBs dose to achieve clinical benefit, but it is unlikely that additional large clinical trials comparing dose strength will be performed. Choice of Angiotensin Receptor Blockers Although different ARBs have different affinity for the AT1 receptors and may have different clinical effects, most ARBs studied in patients with systolic HF demonstrated a reduction in mortality and hospitalization.

Download PDF sample

Rated 4.07 of 5 – based on 36 votes